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PostPosted: Fri Nov 13, 2015 12:34 am 
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New synthetic opioid designer drug found by New York lab Monday, November 09, 2015




Lexington, KY --- The Association of Racing Commissioners International has put all racing regulatory agencies worldwide on notice of a finding by the New York Equine Drug Testing Program of the presence of AH-7921 in post-race samples taken from horses that recently ran at Belmont Park.

This is the first time AH-7921 has been detected by a racing regulatory lab. The drug is one of the Novel Psychoactive Substances that continue to emerge onto the designer drug market. Research has shown that AH-7921 can be as potent as morphine, yet its core molecular structures do not resemble morphine or fentanyl which have been detected in the past by racing regulatory labs.

NPS drugs are believed to be compounded in order to avoid detection by human testing labs.

There is no legitimate reason for AH-7921 to be present in a horse. The New York State Gaming Commission summarily suspended Thoroughbred owner/trainer Roy Sedlacek as a result of the finding.

“Dr. George Maylin and his team should be commended for their persistent attention to emerging threats,” ARCI Chairman Mark Lamberth said, noting that Dr. Maylin has consistently warned of the threat posed by designer drugs and peptides. “This is excellent work on the part of Dr. Maylin and the New York lab.”

Another racing regulatory lab, Industrial Laboratories, was the first to detect the hepta-peptide Dermorphin in a race horse. Dermorphin is a natural opioid that binds as an agonist with high potency and selectivity to mu-opioid receptors. AH-7921 is a selective u-opioid receptor agonist with some effect on the K-receptor as well. Its use can be highly toxic.



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Gaming Commission Rulings Database
Licensee: ROY SEDLACEK
Licensed As: OWNER-TRAINER
Notice Number: MO 347-2015
Racing Type: Thoroughbred
Track: Main Office
Notice Date: 11/06/2015
Ruling Type: Indefinite Suspension
Rule(s): 4002.8, 4002.9(a), 4022.1(f) , 4042.1,4 043.2(h), 4043.4, 4043.5
Ruling Text:

PLEASE TAKE NOTICE that the occupational licenses of you, Roy Sedlacek, to participate in pari-mutuel thoroughbred racing as an owner, trainer, or otherwise are hereby SUSPENDED IMMEDIATELY pending the disposition by the New York State Gaming Commission (“Commission”) of the scheduled hearing before the Commission, or if you refuse such hearing or default in appearing, SUSPENDED until such time as the Commission in its discretion takes further action, including but not limited to license suspension or revocation or refusal to license.
YOU ARE FURTHER NOTIFIED that a hearing in this matter will be held at 9:00 a.m. on Tuesday, November 10, 2015, at Commission offices located at One Broadway Center, Suite 600, Schenectady, New York, at which time you may be represented by counsel and present evidence and arguments on your own behalf.
This action is taken pursuant to Racing, Pari-Mutuel Wagering and Breeding Law ("Racing Law") §§ 220, 245 and 250; 9 NYCRR §§ 4002.8, 4002.9, 4042.1, 4043.2, 4043.4 and 4043.12, and State Administrative Procedure Act § 401, upon a finding of the Commission that the public safety and welfare imperatively require this emergency action because your continued participation in racing is a potential cause of civil unrest and public harm and further could result in an impairment of the public's confidence in pari-mutuel racing in New York state and have an adverse effect upon substantial State and public revenues and revenues to the industry in general generated by pari-mutuel racing, in that, under the present circumstances you lack the general character and fitness for continued participation in pari-mutuel racing, and your continued participation in pari-mutuel racing is presently inconsistent with the public interest, convenience and necessity and with the best interests of racing generally, based upon the circumstances and charges stated more particularly hereinafter.
The disposition of these matters may result in the revocation or suspension of your license, your exclusion from all racetracks in New York State, and the imposition of fines. In particular, at the scheduled and any adjourned dates of your hearing you are notified to show cause why, pursuant to Racing Law §§ 220 and 250, Article 3 of the State Administrative Procedure Act, and Part 4550 of 9 NYCRR, the Commission should not fine you in an amount not exceeding $25,000 per violation, suspend and/or revoke your license(s) to participate in pari-mutuel racing, disqualify the horses you owned that raced in violation of Part 4043 from such race(s) and from any share of the purse in such race(s), and exclude you from all New York State racetracks whether as a licensee, participant, or patron pursuant to Section 220(2) of the Racing Law and the applicable Commission rules at 9 NYCRR, in that:

The horse “Bossmon,” trained by you, ran in the 4th race at Belmont Park on October 11, 2015 with a drug known as AH-7921 (3,4-dichloro-N-[(1-dimethylamino) cyclohexylmethyl]benzamide) having been administered within one week of the scheduled post time of its race, in violation of 9 NYCRR §§ 4043.2(h) and 4043.4;
The horse “Literata,” trained by you, ran in the 2nd race at Belmont Park on October 18, 2015 with a drug known as AH-7921 (3,4-dichloro-N-[(1-dimethylamino) cyclohexylmethyl]benzamide) having been administered within one week of the scheduled post time of its race, in violation of 9 NYCRR §§ 4043.2(h) and 4043.4;
Your character and general fitness are such, based on the foregoing and your history of rule violations, that your participation in pari-mutuel racing is inconsistent with the public interest, convenience and necessity and with the best interests of racing generally, contrary to Racing Law § 220(2) and 9 NYCRR §§ 4002.8 and 4002.9;
You should be excluded from all New York race tracks whether as a licensee, participant, or patron, based on the foregoing, because your conduct at a race track in New York and elsewhere has been detrimental to the best interests of racing and you are guilty of improper, corrupt and fraudulent acts and practices in relation to racing, in violation of Racing Law § 220(2) and 9 NYCRR §§ 4022.12 and 4042.1(f); and
The horses that you owned and that were raced in violation of Part 4043, as set forth above, shall be disqualified from each such race and from any share of the purse in such races, and such shares shall be redistributed among the remaining horses in the race entitled to the same, pursuant to the foregoing statutes and rules and 9 NYCRR § 4043.5.

PLEASE TAKE NOTICE that the hearing will be conducted pursuant to Section 245 of the Racing Law, Article 3 of the State Administrative Procedure Act, and Part 4550 of 9 NYCRR.
PLEASE TAKE NOTICE that you may be represented by counsel, cross-examine witnesses, and present evidence and arguments on your own behalf. Interpreter services will be made available to deaf persons and people who are not English language proficient at no charge but should be requested in writing at least one week before the hearing date, or as soon as reasonably possible. You are responsible to deliver this Notice of Hearing to your attorney, if you have or retain one. This shall be a de novo hearing that may result in the imposition of any legally available penalty including a license suspension or revocation and a fine not to exceed $25,000.
PLEASE TAKE NOTICE TAKE NOTICE that unless you object before the hearing date, the Commission may conduct your hearing using live video conferencing that allows you and each other witness to participate and testify from another location that might be more convenient. To object to live video conferencing, you must contact the hearing officer with concurrent notice to the assigned counsel. The Hearing Officer will determine, after an opportunity for the parties to be heard, whether or not to use live video conferencing. If you choose to participate in your hearing through video conferencing, then you are responsible to be sure that a copy of any physical evidence that you may want to use during testimony or introduce into evidence has been delivered to opposing counsel and the Hearing Officer before the hearing, and that the Hearing Officer is afforded an opportunity to examine any original of such evidence that you may want to introduce into evidence.

PLEASE TAKE NOTICE that the hearing may be adjourned at the discretion of the Hearing Officer for good cause shown upon the request of any party. Requests for adjournments must be submitted as soon as reasonably possible. Absent a serious emergency matter, no requests for adjournments, except for the initial hearing date of November 10, 2015, will be granted within two (2) business days of the scheduled hearing date. To request an adjournment, you must contact the hearing officer at mhoblock@gmail.com, with concurrent notice to the assigned counsel at rick.goodell@gaming.ny.gov, as soon as possible. Requests for adjournments must be in writing and, after the opposing party has an opportunity to be heard regarding a request for adjournment, approved by the Hearing Officer. If you fail to appear at the hearing, then you will be in default, any appeal you filed and request that you made for a hearing may be deemed withdrawn, and the Commission may proceed in your absence with the hearing. Adjournments on consent of all parties are subject to the approval of the Hearing Officer.
PLEASE TAKE FURTHER NOTICE that, if you do not appear at the hearing and have not been granted an adjournment, then the hearing shall take place as scheduled and a decision, including by default, shall be made on the charges. The decision may result in fines, not to exceed twenty-five thousand dollars ($25,000) for each violation, imposed against you; the suspension or revocation of your occupational license(s); the expulsion of you from all pari-mutuel race tracks in New York state; and the disqualification of horses from the races and from any share of the purse in the race in which they participated in violation of Part 4043 of 9 NYCRR.

Suspension Begins: 11/06/2015

NPS drugs are believed to be compounded in order to avoid detection by human testing labs.

There is no legitimate reason for AH-7921 to be present in a horse. The New York State Gaming Commission summarily suspended Thoroughbred owner/trainer Roy Sedlacek as a result of the finding.

“Dr. George Maylin and his team should be commended for their persistent attention to emerging threats,” ARCI Chairman Mark Lamberth said, noting that Dr. Maylin has consistently warned of the threat posed by designer drugs and peptides. “This is excellent work on the part of Dr. Maylin and the New York lab.”

Another racing regulatory lab, Industrial Laboratories, was the first to detect the hepta-peptide Dermorphin in a race horse. Dermorphin is a natural opioid that binds as an agonist with high potency and selectivity to mu-opioid receptors. AH-7921 is a selective u-opioid receptor agonist with some effect on the K-receptor as well. Its use can be highly toxic.

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