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 Post subject: Warren's Styptic Balsam
PostPosted: Fri Jun 26, 2015 1:06 pm 
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This is all I know about a mysterious bleeding remedy from the 19th century that was written about by the famous Eclectic physician, Eli Jones MD. He writes:


Quote:
"I have used a remedy which has never failed me even in the worst cases (of hemorrhage). Every doctor should keep it in his satchel and have no fear of "bleeders". It is the following from Definite Medications, By Eli Jones MD, 1911:

sulfuric acid (by weight).........................5 drams
Oil of Turpentine...................................2 drams
Alcohol...............................................503 minims (20 minims = 1 fluidram, 8.4 fluiddrams = 33.53 ml, 1 fluidram = 4 ml)

Mix: place the acid in the wedgwood mortar, slowly add the turpentine to it, stirring the mixture constantly with the pestle. Then add alcohol (503 minims) in the same manner, constantly stirring until the fumes arise. Place it in a well secured glass stoppered bottle.

If properly made, the mixture will be dark red color like dark blood, but if it is a pale dirty red color it is not fit to use. After a few days, a pellicle forms on the surface which must be broken and the fluid below it used when needed.


Dose: into an ordinary tea cup, place a teaspoonful of brown sugar, add 40 drops of above mixture, mix them thoroughly together, slowly stir in water until the cup is nearly full. This should be immediately swallowed by the patient. Repeat the dose in an hour if it is needed. It was used for hemorrhages from the uterus, stomach, lungs and nose. It is one of the remedies handed down to us by the fathers of the Eclectic School of Medicine.

------------------

I have tried to follow the above instructions, but so far, I am unable to get a product that is deep red and forms a pellicle. Perhaps modern oil of turpentine is no longer what it once was? If anyone out there has any suggestions or experience please comment.

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PostPosted: Fri Jun 26, 2015 1:08 pm 
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King's American Dispensatory, 1898:

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Description.—Official oil of turpentine is "a thin, colorless liquid, having a characteristic odor and taste, both of which become stronger and less pleasant by age and exposure to the air. Specific gravity, 0.855 to 0.870 at 15° C. (59° F.). It boils at 155° to 170° C. (311° to 338° F.). Soluble in three times its volume of alcohol, the solution being neutral or slightly acid to litmus paper; also soluble in an equal volume of glacial acetic acid"—(U. S. P.). It is scarcely soluble in water, but is easily dissolved by chloroform, benzol, ether, etc. Of 90 per cent alcohol, 5 to 12 parts are required for complete solution. Old oil dissolves more easily than fresh oil. It dissolves resins, fixed oils, fats, sulphur, phosphorus, many alkaloids and neutral vegetable principles, and is also a solvent for caoutchouc. Unless purified, oil of turpentine has a slightly acid reaction, owing to the presence of acetic and formic acids. "Bromine or powdered iodine acts violently upon it. When brought in contact with a mixture of nitric and sulphuric acids, it takes fire"—(U. S. P.). It also takes fire when brought into contact with chlorine gas. The oil is inflammable, burning with a fierce, red flame and much black smoke. The various oils of turpentine are optically active; the French oil is markedly laevo-rotatory (-20° to -40°) while the American oil is, as a rule, dextro-rotatory (to + 10°), and in rare cases slightly laevo-rotatory (to -2° 5') (Gildemeister and Hoffmann, loc. cit., p. 320). Oil of turpentine is quite volatile at ordinary temperatures. When exposed to the atmosphere, especially in the presence of moisture, it becomes "ozonized," by absorption of oxygen; it thickens, resinifies, and acquires an acid reaction. In this condition it is a strongly oxidizing agent, due to its containing oxygen in some active form, which is not, however, that of ozone; this has been pointed out by Kingzett (1874) and others. Hydrogen peroxide is one of the active products formed. C. Engler and J. Weissberg have more recently shown (Berichte d. Deutsch. Chem. Ges., 1898, p. 3046) that absolutely dry oil of turpentine absorbs a maximum volume of active oxygen at 100° C. (212° F.), no ozone, nor hydrogen peroxide being formed. The oil thus charged with oxygen retains its active properties for years if it is kept in a dark place. Above this temperature oxidation of the oil takes place. Among the products of oxidation of "ozonized" oil are formic and acetic acids, and camphoric acid (C10H16O4), and small quantities of an aldehyde (C10H16O3) (Schiff, Chem. Zeitung, 1896, p. 361), to which the penetrating odor of old, rancid oil is probably due. (For further details on this subject, see Gildemeister and Hoffmann, Die Aetherischen Oele, p. 300.)

Tests.—Oil of turpentine may be adulterated with, petroleum, paraffin oils, or resin. For their detection, the U. S. P. directs that "if a little of the oil be evaporated in a small capsule on a water-bath, it should leave not more than a very slight residue (absence of petroleum, paraffin oils, or resin)"—(U. S. P.). The lighter petroleum oils reduce the specific gravity of oil of turpentine. The heavier paraffin oils may be recognized by not being volatile with steam, and may be identified in the residue by their indifference toward strong sulphuric or nitric acid. A quantitative separation of mineral oils from oil of turpentine, may be effected (Burton, 1890; Allen, 1890) by means of fuming nitric acid which destroys the latter oil only.

Chemical Composition.—Oil of turpentine consists chiefly of hydrocarbons (terpenes), of the formula C10H16 (Houton-Labillardière, 1817). Among these, pinene, boiling point 155° to 156° C. (311° to 312.8° F.), is the most prominent. Camphene, melting point 50° C. (122° F.), boiling point 159° to 160° C. (318.2° to 320° F.), and probably fenchene, boiling point 154° to 156° C. (309.2° to 312.8° F.), are also regular constituents of oil of turpentine, as well as dipentene, boiling point 175° to 176° C. (347° to 348.8° F.), and sesquiterpenes, boiling at higher temperatures. Certain pine-needle oils also contain the hydrocarbons 1-limonene, dipentene, d-sylvestrene, 1-phellandrene and cadinene, and the fragrant ester bornyl (borneol) acetate.

PINENE occurs in two modifications which are chemically identical. Laevo-pinene (Wallach, 1885; Berthelot's terebentene) is the principal constituent of the French oil of turpentine, while dextro-pinene (Berthelot's australene) occurs, as a rule, in the American oil. It is a colorless, mobile liquid, which, to some extent, resinifies and absorbs oxygen when exposed to the air. It is an unsaturated hydrocarbon with one double bond. Accordingly, it combines, when surrounded by ice, with dry hydrochloric or hydrobromic acid gas, the former yielding the solid compound C10H16.HCl, which has the odor of camphor, hence is called artificial camphor. It melts at 125° C. (257° F.), the bromine compound at 90° C. (194° F.). Pinene is best identified by the melting point of its nitroso-chloride (C10H16.NOCl) which lies at 103° C. (217.4° F.). When heated to 250° to 2700 C. (482° to 518° F.), pinene is changed into dipentene, the inactive (racemic) modification of d- and l-limonene, boiling at 176° C. (348.8° F.). Alcoholic sulphuric acid converts pinene into terpinolene and terpinene. Pinene in prolonged contact with diluted mineral acids, is converted into crystallizable terpin hydrate (C10H18[OH]2H2O) (see Terpini Hydras). By the action of sulphuric and glacial acetic acids, pinene forms the alcohol terpineol (C10H18O), which has the odor of hyacinth and is much used in perfumery. By the action of diluted nitric acid, or chromic acid, pinene is oxidized with formation of the lower fatty acids, and terephtalic (C8H6O4) and terebenic (C7H10O4) acids. By distillation with sulphuric acid, pinene is converted into inactive terebene (see Terebenum).

Action, Medical Uses, and Dosage.—The actions of oil of turpentine are complex. It is irritant, stimulant, cathartic, diuretic, vermifuge, and, in relation to chronic mucous discharges, astringent. Given in large doses it occasions fullness of the head, or giddiness, with a feeling similar to that of intoxication, or a state resembling trance; sometimes it gives rise to pain in the stomach, nausea and vomiting, and more frequently it gives rise to violent strangury, bloody urine, and other symptoms of renal or vesical irritation. In small doses long continued, or when absorbed from its external application, or its vapor inhaled, it produces in the urine an odor resembling that of violets, and sometimes produces strangury. Its most constant effect is purgation, and when this occurs, the other effects seldom present themselves. In medicinal doses it warms the stomach, elevates the temperature of the surface, quickens the pulse, and when given at short intervals, in slight doses, it acts upon the kidneys, causing an increased urinary discharge. In the typhoid stage of febrile diseases, especially when intestinal ulceration is diagnosed from the symptoms, the tongue becoming dry and dark-colored, the skin dry and husky, and tympanites is present, with occasionally mental derangement, small doses given at short intervals and continued for some time, will act as a stimulant and remove all these symptoms. It is supposed, in these instances, to normally influence the ulcerated tissues. It is likewise recommended in neuralgia, chronic rheumatism, dropsy, suppression of urine, worms, especially taenia—tympanitic distension in typhoid fever, peritonitis, or other diseases—chorea, hysteria, croup, colic, jaundice, and in cases where gravel is habitually carried off by copious discharge of lithic acid and lithate of ammonium. It has a tendency to diminish excessive mucous discharges, and has been employed with advantage in chronic catarrh, chronic bronchitis, fetid bronchitis, and pulmonary gangrene (in lung troubles by inhalation as well as internally), chronic dysentery, chronic diarrhoea, chronic inflammation of the bladder, gleet, chronic gonorrhoea, and leucorrhoea. The dose in ordinary cases is from 6 drops to 1/2 fluid drachm, and even to 1 drachm, at intervals of an hour or two in acute and every 3 or 4 hours in chronic diseases. In the course of its action it is absorbed, and imparts its odor to the breath and perspiration. In doses varying from 20 minims to 1 fluid drachm, according to the urgency of the symptoms, and repeated every 3 or 4 hours, it is a most efficacious astringent, and may be used in epistaxis, hematemesis, hemoptysis, and other sanguineous discharges. It may be administered in water, flavored with some agreeable aromatic syrup, or in infusion of matico, in hemoptysis; in the decoctions of uva ursi, epigaea, or eupatorium, etc., in hematuria; or in the decoction or infusion of cinchona, in purpura hemorrhagica. Where much arterial blood has been lost, tincture of chloride of iron will form a valuable adjunct. Combined with castor oil, it is an excellent vermifuge. It probably prevents the formation of biliary calculi. Externally it is a rubefacient, and is used as a counter-irritant in the form of liniment in rheumatism, paralysis, neuralgia, inflammation of internal organs, in the neighborhood of indolent tumors, to chilblains, indolent and erysipelatous ulcers, caries, sloughing, especially from pressure in exhausting diseases, gangrene, chronic inflammation of the edge of the eyelids, and, combined with linseed oil, in recent burns or scalds.

Turpentine, locally and internally, has given signal results in diphtheria and sciatica. In the latter affection about 30 drops, 3 times a day, is the proper dose. It forms a good local application in mammitis, pleurisy, pneumonia, bronchitis, laryngitis, and rhus poisoning. It has given relief in puerperal peritonitis. Its vapor kills the itch insect. Where deafness is occasioned by a scanty or abnormal secretion of cerumen, the oil of turpentine rubbed up with some bland oil, may be passed into the ear, on cotton. In amenorrhoea arising from torpor of the uterine vessels, in obstinate constipation, in tympanites, or when the bowels are distended with flatus, and in ascarides, oil of turpentine used as an injection will frequently be found a superior remedy. From 4 to 8 fluid drachms may be rubbed up with half a pint of water and the yolk of a few eggs, or with some mucilage, and injected into the rectum, where it should be retained for some time. When given internally, it may be administered in simple or aromatized syrup, or rubbed up with sugar, or taken in gin, when not contraindicated, etc.; or it may be triturated with the yolk of egg, gradually adding syrup and essence of cinnamon, with a portion of water. One yolk is sufficient for trituration with every 2 fluid drachms of the oil. In tapeworm, it has been combined with gin, and given in doses of 1 or 2 fluid ounces. As an ordinary vermifuge, 3 or 4 parts of castor-oil may be added to 1 part of the oil of turpentine.

Dr. James Warren has used a preparation for a number of years in the treatment of hemorrhages, with uniform success. It acts both by its sedative power, in diminishing the force of the circulation, and by its astringent qualities, in contact with the bleeding vessels. He is satisfied that no known remedy exerts a more specific power and gives more speedy relief, especially in hemoptysis, hematemesis, epistaxis, and menorrhagia. Dr. Warren terms it Styptic Balsam. It is made as follows: Place sulphuric acid, 5 drachms by weight, in a Wedgewood mortar, and slowly add to it oil of turpentine 2 fluid drachms, stirring it constantly with the pestle; then add in the same manner alcohol 2 fluid drachms, and continue stirring until no more fumes arise, when it maybe bottled, and should be stopped with a ground stopper. It should be prepared from the purest materials; and when made should exhibit a dark but clear red color, like dark blood; but if it be a pale, dirty red, it will be unfit for use. The dose is 40 drops, to be used as follows: into a common-sized teacup put a teaspoonful of brown sugar, thoroughly incorporate the 40 drops by rubbing together, and then slowly stir in water until the cup is nearly full, when the mixture should be immediately swallowed. The dose may be repeated every hour, for 3 or 4 hours, and its use should be discontinued as soon as fresh blood ceases to flow. After standing a few days, a pellicle forms upon the surface of the balsam, which should be broken, and the liquid below it used. If in well-stoppered bottles, age does not deteriorate it (N. Y. Jour. Med.).

NOTE: King's formulation differs from Jones'

sulfuric acid (by weight).........................5 drams
Oil of Turpentine...................................2 drams
Alcohol...............................................2 drams (instead of 8.4 ℨ))

drachm = dram (symbol ℨ)

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PostPosted: Fri Jun 26, 2015 1:10 pm 
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From the American Journal of Pharmacy, Volume 26:



Quote:
FORMULA FOR STYPTIC BALSAM. B) James Warren, M. D.

It is nearly thirty years since I commenced the use of this balsam as a styptic, in the various forms of hemorrhage which are within the domain of medical pathology, and with uniform success. I am satisfied that no remedy now known exerts a more specific power and more speedy relief, especially in hemoptisis, hematemesis, epistaxis, and menorrhagia. It acts both by its sedative power, in diminishing the force of the circulation, and by its astringent qualities, in contact with the bleeding vessels. In the treatment of hemorrhage, neither bloodletting, confinement to the room, suppression of the voice, relaxation from business, nor other precautions are necessary; nor is any auxiliary treatment required, except, perhaps, a dose of Epsom salts, where there is evidence that blood has been swallowed.

Ordinary exercise in the open air is decidedly preferable to inaction; and wherever there are premonitory symptoms of a return of hemorrhage, it has always exerted a prophylactic power when promptly used; and by this early resort to the remedy, many radical cures have been effected.

The following is the formula and the method of using it:—
ji. Acid. Sulphuric, (by weight,) 3V. •
Spts. Terebinth.
Spts. Vin. Rect. aa.

Place the acid in a Wedgewood mortar, and add the turpentine slowly, stirring it constantly with the pestle; then add the alcohol in the same manner, and continue stirring it until no more fumes arise, when it may be bottled, and should be stopped with a ground stopper. It should be prepared from the purest materials; and when done, it should exhibit a dark but clear red color, like dark blood; but if it be a pale, dirty red, it will be unfit for use. The dose is 40 drops, and the method of using it is as follows: Put a teaspoonful of brown sugar in a commonsized teacup, and rub in 40 drops of the balsam until it is thoroughly incorporated, and then slowly stir in water until the cup is nearly full, when it should be immediately swallowed. This dose may be repeated at intervals of an hour, until three or four doses are taken, if necessary; and its use should be discontinued when fresh hlood ceases to flow. After standing a few days, a pellicle forms upon the surface of the balsam, which should be broken, and the liquid below it used. It does not deteriorate by age, if tightly stopped.—

N. T. Journal of Medicine, from K Y. Med. Times.

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PostPosted: Fri Jun 26, 2015 1:11 pm 
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Old time treatments for bleeding:

Quote:
Internally, astringents should be given, as ten or twenty grains every ten or twenty minutes, of a mixture of equal parts of Alum, Geranium, and Charcoal; or, N itre ten grains, Alum five grains, Kino one grain and a half, may be triturated together for a dose, repeating it three or four times a day. The Oils of Fireweed, and Flcabane, will frequently be found serviceable. I have frequently succeeded in checking the flow by administering every hour or two, a powder composed of Capsicum five grains, Opium half a grain, Ipecacuanha one grain; mix. A combination of Tincture of Cinnamon bark and Tincture of Yarrow, equal parts, taken in table-spoonful doses, and repeated three times a day, has often proved serviceable; a little Oil of Cinnamon may be added to cover its disagreeable taste. Warren’s Styptic Balsam has been found prompt and efiectual in many instances. In quite a number of cases recently, I have found a Tincture of the inner bark of Cotton root, made in Sweet Spirits of N itre, a very effectual remedy, in doses of from thirty to sixty drops, three, four, or five times a day.

lVhile using either of the above remedies, the patient may drink freely of some astringent decoction, as, one made of equal parts of Beth root, Blackberry root, and Geranium; or, other vegetable astringents. If the flow be very profuse, Hemastasis may be adopted with advantage. If much pain be present, a mixture of Sulphate of Morphia one-fourth or oneeighth of a grain, Capsicum five grains, Rosin five grains, may be administered every two or three hours in some Blackberry Syrup.

The astringent decoction above named may be continued, or some other used as a substitute, and the following may be administered daily:—Take of Sulphate of Quinia ten grains, Extract of Belladonna three grains, Extract of Rhatany forty grains; mix, and divide into twenty pills. The dose is one pill, to be repeated three times a day.

As in active menorrhagia, various agents may be required before any benefit will be experienced. In very mild cases, the Tincture of Cinnamon given in teaspoonful doses every hour or two, in a wineglassful of sweetened water, will be found of service. The Tincture of Cottonroot bark made in Sweet Spirits of Nitre, as named in the preceding form, will be found of great advantage in many instances. The preparation of Nitre, Alum, and Kino, named in the preceding variety, will also prove beneficial. Frequently, even in some very severe attacks of menorrhagla, I have derived much benefit from the use of the Tincture of Muriate of Iron, in doses of from fifteen to twenty drops, every half-hour, hour, or two hours, according to the urgency of the case, administering each dose in about half a gill of water. Warren's Styptic Balsam has been used with good results in many cases; and the following will prove very effectual in arresting the flow, with many females:—Take of Tincture of Cinnamon, Tincture of Rhatany, Spirits of Turpentine, each, equal parts: mix. The dose is from half a teaspoonful to a tcaspoonful, every hour or two, in some Port Wine, or other convenient vehicle. A-nother very valuable preparation, is composed of Tincture of Cottonroot bark, Tincture of Ergot, and Tincture of Cinnamon, each, equal parts: mix. Dose, the same as the preceding.

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PostPosted: Fri Jun 26, 2015 1:12 pm 
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This and following articles on turpentine is dedicated to my great-grandmother, Leone Jones, who was the wife of my great-grandfather, Charles Jones MD. It has come down in my family lore that her favorite remedy was turpentine and it is with love & respect that I document turpentine's usefulness in her memory. Doug



From the 1918
Indianapolis Medical Journal, Volume 21

The Value of Turpentine Hemorrhage




Quote:
TURPENTINE IN HEMORRHAGE.

It is difficult to determine the possibilities of turpentine as a therapeutic agent. As an internal remedy as well as a topical one it has a wide range. In typhoid fever after hemorrhage we have always used it in the form of an emulsion; but not during the hemorrhage. An abstract in the Medical Sentinel for March is of interest.

Allan, in The Practitioner, very properly points out that enthusiasm for testing out new drugs often leads to neglect of older remedies, and this sometimes results in useful therapeutic agents fallIng into desuetude. The value of turpentine applied locally for hemorrhage is well known, yet it Is not so frequently employed as It might be. This Is rather surprising because turpentine is generally available, or at any rate is easily obtainable. Allan has many times demonstrated its local utility in hemorrhage in practice, and he can best illustrate this point by quoting a few cases.

A workman had an oblique portion of the Up of one of his fingers removed by the blade of a cutting machine. There was considerable hemorrhage, but no actual bleeding point which could be ligatured was to be seen. There was simply capillary oozing, which gauze soaked in hydrogen peroxide, etc., failed to check. When Allan saw the case he suggested the application of gauze wrung out of turpentine, and this was successful in stopping the bleeding. In another case a soldier had several teeth extracted and the after-bleeding, especially from one tooth socket, seemed uncontrollable. The bleeding was so severe that the man was admitted to hospital instead of being returned to his depot. The customary styptics were applied locally without success, but when turpentine was tried the hemorrhage ceased. Another youth had a submucous resection of the septum nasi done and, contrary to the usual experience, persistent capillary oozing set in, which was not checked until the nasal cavities had been packed with gauze soaked In turpentine. In a little boy, who was afterwards discovered to be a hemophiliac subject, an abscess was opened in the thigh, and from the wall of the abscess cavity hemorrhage occurred which proved difficult to check. The best local application in this case also was gauze packing soaked in turpentine.

There Is one practical point in using turpentine for the purposes indicated, and that is, the gauze should not be applied saturated with superfluous fluid. The gauze should be well soaked In the turpentine, but prior to application to the affected part It should be thoroughly squeezed dry, otherwise results will be disappointing. Allan has employed turpentine with success when other drugs have failed, and considers this homely remedy deserves fuller recognition in the routine treatment of capillary hemorrhage. S. E. E.

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PostPosted: Fri Jun 26, 2015 1:13 pm 
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From THE MEDICAL WORLD, Vol 17 (1899)



Quote:
Turpentine, in 5 or 10 drop doses, repeated every hour or two, is the best remedy in cases of putrid scarlet fever. In a very severe epidemic of scarlet fever of a low typhoid type, the throat symptoms were exceedingly severe, color of skin almost black and mottled purple, throat and tongue much swollen, thick, sticky mucus in the mouth and throat, tonsils immensely enlarged, pupils fully dilated. I used turpentine made in emulsion with yelk of egg and powdered gum acacia, each teaspoonful containing 10 drops, repeated every hour, in the worst cases. The color of the skin changed and the eruption came out in a natural form. Besides, the intensely high temperature (105° F.), fell in ten hours to 101 °, and pulse rose in strength and stability of action. In 48 hours all the symptoms had very much improved. The odor that came from the patients' bodies during the worst stage was very offensive; the turpentine certainly removed this stench, and the urine that was nearly supprest was increast in quantity in 24 hours. This was one of the encouraging signs.



Turpentine is a certain remedy to arrest hemorrhage, especially the flow of blood from capillary vessels. I have seen it quickly stop bleeding from bones that occurred after operations, after all other known remedies had failed. I arrested hemorrhage that flowed nearly 24 hours from a woman's breast, after a large abscess had been opened and pus let out. The bleeding was persistent and copious; all efforts and remedies had failed to stop it. Finally, I saturated a piece of fine sponge with oil of turpentine and introduced it into the cavity; in five minutes the hemorrhage ceast. The walls of the abscess granulated rapidly, leading to a speedy cure, but the pain was severe at first. Every physician is aware of the very great value of turpentine in tympanites in the middle and last stage of typhoid fever. But it often fails to cure the tympanites, because the dose is too small.

I have often increast the dose from 10 drops to a teaspoonful, and in some cases have administered a tablespoonful after smaller doses had failed, with positive aud beneficial results. I have seen only one case in which turpentine in typhoid fever in large doses caused untoward symptoms when it was administered for tympanites.

When the mucous membrane in typhoid fever secretes a large quantity of mucus along with the "pea-soup" or " scrapedbeef" stools, recurring often, turpentine is the remedy, tho there be no tympanites. In mucous diarrheas and in those septic diseases accompanied by glazed, dry, cracked, red tongue, with sordes on teeth and gums, turpentine is the remedy; and it is best given in emulsion made with yelk of egg and glycerin. The dose should be 5 to 10 drops in 20 drops of emulsion, repeated every hour or two. I regard turpentine in these cases as nearly specific. Yet close attention must be given lest it cause irritation of the genito-urinary tract. As soon as any such symptom presents, stop the medicine and give plenty of mucilaginous drinks.

Singular to say, turpentine is a valuable diuretic in what we call atonic states of the system, and one of the symptoms is much diminisht action of the kidneys. There is not much if any fever, the heart


beats feebly and the frequency is increast with some irregularity of the rhythm. In these cases, 5 to 10 drops of turpentine stimulates the kidneys to increast action, the heart beats stronger and the rhythm is regular. In fact I regard turpentine, in proper doses, as a fine tonic to the mucous membranes when this tissue is suffering from chronic inflammation and an abnormal secretion of mucus.

Before I close I offer a formula I use often with success, in aborting boils, bubos that follow soft chancre, and white swellings. It is rubifacient, anodyne and anesthetic. It can be taken internally in the cramp colics and painful intestinal troubles so frequent in summer, and for which Dr. Squibb's diarrhea and cholera morbus medicine is used with much confidence by the average run of doctors:

Oil turpentine dr. vj

Chloroform dr. vj

Chloral hydrate ... .dr. iij

Gum camphor dr. ijss

Mix, dissolving all the ingredients. It is good externally and internally. Turpentine is a powerful antiseptic and the others are noted pain-killers.

The dose is to 10 to 20 drops in water. Children can take 3 to 5 drops. Repeat as often as required.

Dr. Jos. Adolphus. South Atlanta, Ga.

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PostPosted: Fri Jun 26, 2015 1:15 pm 
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From the Medical and Surgical Reporter (1880)

Uterine Haemostatics:

Quote:
Dr. Atthill said that he would confine his remarks to the means of arresting hemorrhages from the unimpregnated uterus. He said that the most common causes giving origin to uterine hemorrhage, unconnected with the actual existence of pregnancy, were: 1. The various forms of cancer; 2. Tumors of the uterus; 3. Imperfect involution of the uterus after labor or abortion; 4. Granular erosion of the cervix uteri; 5. A granular condition of the intra-uterine surface; 6. Retention of a portion of the ovum after abortion. 1. Cancer was placed first on the list of causes, because its treatment by the administration of Chian turpentine, as advocated by Mr. John Clay, of Birmingham, had attracted general attention. Dr. Atthill's opinion of the drug as a haemostatic, in some cases of cancer, was very favorable; but he could not confirm to the full extent Mr. Clay's views as to its curative powers in malignant disease of the uterus. It seemed to exercise its greatest power in cases of epithelioma of the cervix, and to have comparatively little influence in the medullary form of the disease. The value of turpentine in cancer of the uterus seemed to be mainly due to its action in diminishing the blood-supply. Dr. Atthill related the case of a lady who came under his care in September, 1879, suffering from a severe attack of uterine hemorrhage, which proceeded from an epithelioma of the cervix uteri. The hemorrhage was checked by the application of the strong solution of perchloride of iron; but, as the disease steadily progressed, the diseased structures were removed with the scoop and knife, on December 1st. The patient rapidly recovered; but in February the hemorrhage recurred, and the disease was found to have extended into the cavity of the uterus. The diseased mass was removed; but the hemorrhage continued in spite of the use of perchloride of iron. In March, Dr. Atthill began to administer pills of three grains of Chian turpentine with two of sulphur, eight to be taken daily. For some time the hemorrhage was much lessened, and almost disappeared; but lately there had been a return of the bleeding to an alarming extent. The patient had taken the Chian turpentine daily, from the time of its first prescription. The small supply of Chian turpentine, and the difficulty of obtaining it pure, were serious objections to its use. Dr. Atthill believed that a pure oil of turpentine, administered in from ten- to twentydrop doses, three or four times a day, was, as a haemostatic, quite as good; and that, if carefully rubbed up with powdered gum arabic or tragacanth, it was likely to agree with most patients. He had also administered the confection of turpentine with advantage. 2. To restrain the hemorrhage from fibrous tumors, the injection into the uterus of the liquor ferri perchloridi, and of the tincture of iodine, had been advocated. This method was sometimes followed by satisfactory results; but it was not absolutely safe, and, unless care were taken to provide a free exit for the fluid injected, either by previously dilating the cervix uteri or by using a double cannula, serious results might follow. The injection of hot water in such cases was a far safer method of restraining the hemorrhage. Incising the cervix was often useful, in being followed by a diminution in the hemorrhage, and by relief from pain; and at the same time it permitted the introduction into the uterus of a tube of moderate size and the free return of the hot water, which should be injected at a temperature of about 110° Fahr. Another simple and often effectual method of applying heat was the use of Chapman's spinal hot water bags. Of drugs, none could equal ergot in its power of restraining the hemorrhage depending on fibrous tumors. It was most effective when administered hyp jdermically. 3. Imperfect involution of the uterus implied, primarily, a relaxed state of the muscular tissue of the organ, and an unduly distended condition of the uterine vessels; and, also, in most cases, an unhealthy condition of the intra-uterine mucous membrane. When the latter existed, it must be cured by treatment directed to the intra-uterine surface. To check the hemorrhage at the time of its occurrence, hot water was a safe plan of treatment, and generally easily carried out. Ergot, quinine, and strychnine were, in cases of imperfect involution of the uterus, indirect haemostatics. In the chronic form of the affection Dr. Atthill had administered Chian turpentine with benefit. 4. Hemorrhage due to a granular condition of the vaginal aspect of the cervix might be arrested by the direct application to the bleeding surface of almost any astringent; but, to prevent its recurrence, a healthy condition of the cervix must be brought about by the free application of some strong caustic. 5. The retention of a portion of the ovum after abortion sometimes gave rise to very troublesome hemorrhage. In such cases, dilatation of the uterus and removal of the retained portion by a curette might be performed unless contraindicated, but it was liable to give rise to cellulitis and even peritonitis; and Dr. Atthill, therefore, strongly recommended in such cases, at least as a preliminary measure, the syringing out the uterus with hot water. He had no faith in the administration of astringents by the mouth, in cases of uterine hemorrhage depending on the causes which he had enumerated. In conclusion, he suggested that the most important questions for discussion, in connection with the subject of uterine haemostatics, were these: 1. What is the value of Cbian turpentine in arresting hemorrhage in cases of cancer of the uterus? 2. Is Chian turpentine the only variety of the drug of use in such cases? 3. In what other forms of uterine hemorrhage is the administration of turpentine indicated? 4. What ia the value of the intra-uterine injection of hot water: (a) in cases of hemorrhage depending on the existence of fibrous tumors of the uterus; (6) in cases of imperfect involution of the uterus; (c) where portions of the ovum have been retained after abortion?

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