Username:
Password:
Log me on automatically each visit
 
 
It is currently Tue Nov 12, 2019 6:41 am
Post a new topic Post a reply  [ 1 post ]   
Author Message
 Post subject: Disulfiram for Lyme
PostPosted: Tue Aug 06, 2019 11:46 am 
Site Admin
User avatar

Joined: Wed May 27, 2015 10:20 am
Posts: 428
This may also be useful in an equine infection of Lyme like bacteria:



https://www.lymedisease.org/disulfiram-kinderlehrer/

Quote:
Scientists recently discovered that disulfiram is effective in the lab setting at killing the microbes that cause Lyme disease. Disulfiram is more commonly known as "Antabuse". It is an FDA-approved compound used to assist alcoholics in resisting alcohol consumption. Most remarkable is that disulfiram was effective at killing not only the actively replicating Lyme bacteria (ie, the ones that are typically killed by several antibiotics) but also the relatively dormant or quiescent Lyme bacteria (these are called "drug-tolerant persisters") - these latter spirochetes are the ones that may account for the development of chronic Lyme disease symptoms.


Dosage seems to be around two 500mg tablets per day for 8 weeks.

----------



ANTABUSE®
(disulfiram) Tablets USP

Possible Side Effects:

OPTIC NEURITIS, PERIPHERAL NEURITIS, POLYNEURITIS, AND PERIPHERAL NEUROPATHY MAY OCCUR FOLLOWING ADMINISTRATION OF DISULFIRAM.

Multiple cases of hepatitis, including both cholestatic and fulminant hepatitis, as well as hepatic failure resulting in transplantation or death, have been reported with administration of disulfiram.

Occasional skin eruptions are, as a rule, readily controlled by concomitant administration of an antihistaminic drug.

In a small number of patients, a transient mild drowsiness, fatigability, impotence, headache, acneform eruptions, allergic dermatitis, or a metallic or garlic-like aftertaste may be experienced during the first two weeks of therapy. These complaints usually disappear spontaneously with the continuation of therapy, or with reduced dosage.

Psychotic reactions have been noted, attributable in most cases to high dosage, combined toxicity (with metronidazole or isoniazid), or to the unmasking of underlying psychoses in patients stressed by the withdrawal of alcohol.

Top
OfflineProfileReply with quote
 
Display posts from previous:  Sort by  
Post a new topic Post a reply  [ 1 post ] 
 

Who is online

Users browsing this forum: No registered users and 0 guests

You cannot post new topics in this forum
You cannot reply to topics in this forum
You cannot edit your posts in this forum
You cannot delete your posts in this forum
You cannot post attachments in this forum
 
Search for:
Jump to:  
cron